30 April 2022:	ESPRESSO server will be stopped from 7:00 to 18:00 on April 30, 2022, because of electric work.
27 April 2021:	ESPRESSO server will be stopped from 7:00 to 18:00 on April 29, 2021, because of electric work.
18 Dec 2020:	ESPRESSO server will be stopped from 18:00 on December 24, 2020 to 9:00 on January 7, 2021, because of electric work in the server room.
1 Dec 2020:	ESPRESSO server will be stopped from 18:00 on December 5 to 9:00 on December 7, 2020, because of electric work in the server room.
19 Apr 2019:	ESPRESSO server will be stopped from 7:00 on April 27 to 8:00 on May 7, 2019.
1 Jun 2018:	The ESPRESSO URL will move to "http://cblab.my-pharm.ac.jp/ESPRESSO/" since August 2018.
25 July 2018:	ESPRESSO server will be stopped in August 2018, because of system migration.
21 Jun 2018:	ESPRESSO server will be stopped from 9:30 to 12:00 on June 25.
25 Apr 2018:	ESPRESSO server will be stopped on April 28.
4 Apr 2017:	ESPRESSO server will be stopped on April 29.
21 Apr 2016:	ESPRESSO server will be stopped on April 30.
14 Jul 2015:	Pfam database is updated to Pfam 28.0.
24 Jun 2015:	The ESPRESSO (ver 1.2) is released at Meiji Pharmaceutical University.
1 Sep 2012:	The models of property based method were updated.
4 Aug 2011:	The release of ESPRESSO (ver 1.1) server. The prediction models were updated.
29 Jan 2011:	Protein solubility for A Brevibacillus expression system is added.
10 Jun 2010:	A motif dataset for solubility in E. coli is updated.
03 Mar 2010:	A serious bug in the motif based prediction for protein solubility in E.coli is fixed.
24 Feb 2010:	The mode that observes the relationship between motifs and model structure is added.
19 Feb 2010:	The results of disordered region prediction and BLAST for PDB are added.
09 Feb 2010:	The statistical page is added.
09 Dec 2009:	Bug fixing.
01 Dec 2009:	The release of ESPRESSO (ver 1.0) web server.